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To be included, research needed to report abstinence from cigarettes at six months or longer and/or knowledge on adverse events or other markers of safety at one week or longer. Electronic cigarettes are handheld electronic vaping devices which produce an aerosol formed by heating an e-liquid. People who smoke report utilizing ECs to cease or scale back smoking, however some organisations, advocacy teams and policymakers have discouraged this, citing lack of evidence of efficacy and safety. People who smoke, healthcare suppliers and regulators need to know if ECs may help individuals stop and if they’re secure to make use of for this purpose. There is moderate-certainty evidence that ECs with nicotine improve quit charges compared to ECs with out nicotine and in comparison with NRT. Evidence comparing nicotine EC with traditional care/no therapy also suggests profit, however is less certain. More research are wanted to confirm the degree of effect, …